Reference Determination Content
Suggested draft · fictitious patient
Vaccine-Induced Thrombotic Thrombocytopenia
Evidence
The evidence that I have considered in making this decision includes:
- Formal Claim with supporting statements;
- A Statement of your Service from the Department of Defence;
- Copies of your Service Medical Records.
- A Diagnostic Assessment by Dr Thomas Perkins, General Practitioner, Veterans Health Centre, dated 9 September 2025;
- A Diagnosis Form (D9287) by Dr Thomas Perkins, General Practitioner, Veterans Health Centre, dated 9 September 2025;
- A pre-deployment medical examination and full blood count by the medical officer, dated 22 March 2021;
- An immunisation record by the base health centre, dated 23 March 2021;
- A role 1 treatment record by the medical officer, Middle East, dated 5 April 2021;
- An emergency admission by the CT venogram and pathology, Coalition hospital, Middle East, dated 8 April 2021;
- Inpatient progress notes and CT brain and abdomen by the coalition hospital, Middle East, dated 10 April 2021;
- An aeromedical evacuation record by the aeromedical evacuation team, dated 11 April 2021;
- A haematology consultation (anti-PF4 ELISA and platelet activation assay) by the haematologist, dated 12 April 2021;
- An MRI brain and MR venography by the radiologist, dated 13 April 2021;
- A neurology review and MRI by the neurologist, dated 14 October 2021.
Your service
I have identified that you have the following service:
Australian Defence Force service between :
6 September 1993 and 30 September 2022
Vaccine-Induced Thrombotic Thrombocytopenia
You have stated that your condition was caused by:
- having received an adenovirus vector coronavirus disease 2019 (COVID-19) vaccine within the 100 days before the clinical onset of vaccine-induced thrombotic thrombocytopaenia
Diagnosis: Vaccine-Induced Thrombotic Thrombocytopenia
Basis of diagnosis: The diagnosis was made in the Diagnostic Assessment by Dr Thomas Perkins dated 9 September 2025, and is supported by a haematology consultation (anti-PF4 ELISA and platelet activation assay) by the haematologist, dated 12 April 2021.
I am satisfied this is the appropriate diagnosis.
In determining your claim for this condition, I have applied the SOP:
Statement of Principles concerning Vaccine-Induced Thrombotic Thrombocytopaenia (Reasonable Hypothesis) (No. 33 of 2022)
which sets out the factors that can connect the condition with service.
I am satisfied that you have met the following factor:
- having received an adenovirus vector coronavirus disease 2019 (COVID-19) vaccine within the 100 days before the clinical onset of vaccine-induced thrombotic thrombocytopaenia
I have noted your contention as to the cause of this condition. The available evidence indicates, I have noted your contention to the cause of your condition. Your service medical records indicate that you presented to the health facility with a severe, constant headache, worse lying down and on straining, with nausea, unrelieved by simple analgesia on 5 April 2021.
The diagnosis was confirmed by a haematologist on 12 April 2021. You had thrombosis of the cerebral venous sinuses on CT venography on 8 April 2021 in association with a low platelet count of 42 x 10^9/L, and you had had no exposure to heparin within the 30 days before onset, meeting the Statement of Principles definition of vaccine-induced thrombotic thrombocytopaenia. The diagnosis was supported by a D-dimer above 20 mg/L, a low fibrinogen of 1.2 g/L, a strongly positive anti-PF4 ELISA and a positive platelet activation assay.
This has then led to further investigations and the diagnosis of your condition of Vaccine-Induced Thrombotic Thrombocytopenia. I have accepted your condition of Vaccine-Induced Thrombotic Thrombocytopenia.
Having considered your service records and the available medical evidence, I am satisfied the SOP is met and that this condition is related to your wartime service.
I have therefore accepted that this condition is related to your service with effect from 2 April 2021.
Vaccine-Induced Thrombotic Thrombocytopenia (Worsening)
Evidence
The evidence that I have considered in making this decision includes:
- Formal Claim with supporting statements;
- A Statement of your Service from the Department of Defence;
- Copies of your Service Medical Records.
- A Diagnostic Assessment by Dr Thomas Perkins, General Practitioner, Veterans Health Centre, dated 9 September 2025;
- A Diagnosis Form (D9287) by Dr Thomas Perkins, General Practitioner, Veterans Health Centre, dated 9 September 2025;
- A pre-deployment medical examination and full blood count by the medical officer, dated 22 March 2021;
- An immunisation record by the base health centre, dated 23 March 2021;
- A role 1 treatment record by the medical officer, Middle East, dated 5 April 2021;
- An emergency admission by the CT venogram and pathology, Coalition hospital, Middle East, dated 8 April 2021;
- Inpatient progress notes and CT brain and abdomen by the coalition hospital, Middle East, dated 10 April 2021;
- An aeromedical evacuation record by the aeromedical evacuation team, dated 11 April 2021;
- A haematology consultation (anti-PF4 ELISA and platelet activation assay) by the haematologist, dated 12 April 2021;
- An MRI brain and MR venography by the radiologist, dated 13 April 2021;
- A neurology review and MRI by the neurologist, dated 14 October 2021.
Your service
I have identified that you have the following service:
Australian Defence Force service between :
6 September 1993 and 30 September 2022
Vaccine-Induced Thrombotic Thrombocytopenia (Worsening)
You have stated that the worsening of your condition was caused by:
- inability to obtain appropriate clinical management for vaccine-induced thrombotic thrombocytopaenia
Diagnosis: Vaccine-Induced Thrombotic Thrombocytopenia (Worsening)
Basis of diagnosis: The diagnosis was made in the Diagnostic Assessment by Dr Thomas Perkins dated 9 September 2025, and is supported by a haematology consultation (anti-PF4 ELISA and platelet activation assay) by the haematologist, dated 12 April 2021.
I am satisfied this is the appropriate diagnosis.
In determining your claim for this condition, I have applied the SOP:
Statement of Principles concerning Vaccine-Induced Thrombotic Thrombocytopaenia (Reasonable Hypothesis) (No. 33 of 2022)
which sets out the factors that can connect the condition with service.
I am satisfied that you have met the following factor:
- inability to obtain appropriate clinical management for vaccine-induced thrombotic thrombocytopaenia
I have noted your contention as to the cause of this condition. The available evidence indicates, I have noted your contention to the cause of your condition. Your service medical records indicate that you presented to the health facility with a severe, constant headache, worse lying down and on straining, with nausea, unrelieved by simple analgesia on 5 April 2021.
The diagnosis was confirmed by a haematologist on 12 April 2021. You had thrombosis of the cerebral venous sinuses on CT venography on 8 April 2021 in association with a low platelet count of 42 x 10^9/L, and you had had no exposure to heparin within the 30 days before onset, meeting the Statement of Principles definition of vaccine-induced thrombotic thrombocytopaenia. The diagnosis was supported by a D-dimer above 20 mg/L, a low fibrinogen of 1.2 g/L, a strongly positive anti-PF4 ELISA and a positive platelet activation assay.
After the condition arose, it was worsened during your service. On non-warlike service in the Middle East from 02 to 11 April 2021 you could not obtain recognition of the condition, anti-PF4 testing, haematology advice, intravenous immunoglobulin or a non-heparin anticoagulant.
This has then led to further investigations and the diagnosis of your condition of Vaccine-Induced Thrombotic Thrombocytopenia (Worsening). I have accepted your condition of Vaccine-Induced Thrombotic Thrombocytopenia (Worsening).
Having considered your service records and the available medical evidence, I am satisfied the SOP is met and that the worsening of this condition is related to your wartime service.
I have therefore accepted that the worsening of this condition is related to your service with effect from 10 April 2021.

