Charcot-marie-tooth disease
Meaning of charcot-marie-tooth disease: For the purposes of this Statement of Principles, Charcot-Marie-Tooth disease means one of a group of genetic disorders of myelin structure or axon function which results in chronic peripheral motor and sensory neuropathies.
Reasonable Hypothesis (RH) — Statement of Principles No. 88 of 2023
At least one of the following factors must as a minimum exist before it can be said that a reasonable hypothesis has been raised connecting Charcot- Marie-Tooth disease or death from Charcot-Marie-Tooth disease with the circumstances of a person's relevant service:
- (1)taking a drug that cannot be ceased or substituted in the long term and which is associated in the individual with the clinical worsening of Charcot-Marie-Tooth disease during drug therapy and either: (a) the improvement of Charcot-Marie-Tooth disease within 3 months of discontinuing or tapering drug therapy; or (b) the clinical worsening of Charcot-Marie-Tooth disease on rechallenge with the same drug or another drug from the same class of drugs; and where the drug was being taken at the time of the clinical worsening of Charcot-Marie-Tooth disease;
- (2)inability to obtain appropriate clinical management for Charcot-Marie- Tooth disease before the clinical worsening of Charcot-Marie-Tooth disease;
Aggravation-only factors: the factors in subsections 9(1) and 9(2) apply only to material contribution to, or aggravation of, the condition where it was suffered or contracted before or during (but did not arise out of) the person’s relevant service.
Balance of Probabilities (BoP) — Statement of Principles No. 89 of 2023
1 factors
At least one of the following factors must exist before it can be said that, on the balance of probabilities, Charcot-Marie-Tooth disease or death from Charcot-Marie-Tooth disease is connected with the circumstances of a person's relevant service:
- (1)inability to obtain appropriate clinical management for Charcot-Marie- Tooth disease before the clinical worsening of Charcot-Marie-Tooth disease;
Aggravation-only factors: the factors in subsection 9(1) apply only to material contribution to, or aggravation of, the condition where it was suffered or contracted before or during (but did not arise out of) the person’s relevant service.








