Eosinophilic oesophagitis
Meaning of eosinophilic oesophagitis: For the purposes of this Statement of Principles, eosinophilic oesophagitis means a chronic, immune-mediated oesophageal disease, characterised by symptoms related to oesophageal dysfunction, together with eosinophil-predominant inflammation of the oesophageal epithelium.
Reasonable Hypothesis (RH) — Statement of Principles No. 29 of 2022
At least one of the following factors must as a minimum exist before it can be said that a reasonable hypothesis has been raised connecting eosinophilic oesophagitis or death from eosinophilic oesophagitis with the circumstances of a person's relevant service:
- (1)taking an average of at least 600 milligrams of aspirin per day for the desensitisation of aspirin-exacerbated respiratory disease for at least the 3 months before the clinical onset of eosinophilic oesophagitis;
- (2)taking carbamazepine daily for at least the 7 days before the clinical onset of eosinophilic oesophagitis;
- (3)having oral or sublingual allergen immunotherapy at the time of the clinical onset of eosinophilic oesophagitis;
- (4)undergoing organ or tissue transplantation, excluding corneal transplant, before the clinical onset of eosinophilic oesophagitis;
Note: organ or tissue transplantation is defined in the Schedule 1 - Dictionary.
- (5)taking an average of at least 600 milligrams of aspirin per day for the desensitisation of aspirin-exacerbated respiratory disease for at least the 3 months before the clinical worsening of eosinophilic oesophagitis;
- (6)taking carbamazepine daily for at least the 7 days before the clinical worsening of eosinophilic oesophagitis;
- (7)having oral or sublingual allergen immunotherapy at the time of the clinical worsening of eosinophilic oesophagitis;
- (8)undergoing organ or tissue transplantation, excluding corneal transplant, before the clinical worsening of eosinophilic oesophagitis;
Note: organ or tissue transplantation is defined in the Schedule 1 - Dictionary.
- (9)inability to obtain appropriate clinical management for eosinophilic oesophagitis;
Aggravation-only factors: the factors in subsections 8(5) to 8(9) apply only to material contribution to, or aggravation of, the condition where it was suffered or contracted before or during (but did not arise out of) the person’s relevant service.
Balance of Probabilities (BoP) — Statement of Principles No. 30 of 2022
7 factors
At least one of the following factors must exist before it can be said that, on the balance of probabilities, eosinophilic oesophagitis or death from eosinophilic oesophagitis is connected with the circumstances of a person's relevant service:
- (1)taking an average of at least 600 milligrams of aspirin per day for the desensitisation of aspirin-exacerbated respiratory disease for at least the 3 months before the clinical onset of eosinophilic oesophagitis;
- (2)taking carbamazepine daily for at least the 7 days before the clinical onset of eosinophilic oesophagitis;
- (3)having oral or sublingual allergen immunotherapy at the time of the clinical onset of eosinophilic oesophagitis;
- (4)taking an average of at least 600 milligrams of aspirin per day for the desensitisation of aspirin-exacerbated respiratory disease for at least the 3 months before the clinical worsening of eosinophilic oesophagitis;
- (5)taking carbamazepine daily for at least the 7 days before the clinical worsening of eosinophilic oesophagitis;
- (6)having oral or sublingual allergen immunotherapy at the time of the clinical worsening of eosinophilic oesophagitis;
- (7)inability to obtain appropriate clinical management for eosinophilic oesophagitis;
Aggravation-only factors: the factors in subsections 8(4) to 8(7) apply only to material contribution to, or aggravation of, the condition where it was suffered or contracted before or during (but did not arise out of) the person’s relevant service.
